Large amount of SER is found in cells storing
High-Yield Explanation
Cholesterol(lipid) is synthesized in the smooth endoplasmic reticulum from acetyl CoA. The rate-limiting step is the formation of mevalonate from 3-hydroxy 3-methylglutaryl-CoA by HMG CoA reductase and lanosterol is the first cyclic intermediate.SER synthesise lipids whereas RER synthesise proteinsRef: Harper biochemistry: 267