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General Medicine General b5245f2d

40 yr old man presents with single erythematous plaque on the penis. Histologic examination reveals dysplastic cells throughout the epidermis . All of the following are true about the disease, patient is suffering from except?

A
Intact basement membrane
B
Occurs in older uncircumcised males
C
No transformation to invasive carcinoma
D
Strong association with HPV types 16 and 18

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