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Pathology Adrenal Gland b4bd258e

A 26-year-old primigravida develops gestational diabetes and remains hyperglycemic during the remainder of her pregnancy. Which of the following abnormalities in the newborn child is likely related to the maternal hyperglycemia?

A
Ambiguous genitalia
B
Cretinism
C
Increased bih weight
D
Sheehan syndrome
High-Yield Explanation
- The most common effect of maternal diabetes mellitus on child is increased bih weight, i.e macrosomia. - This also increases likelihood of obstetric complications, including need for cesarean section & increased likelihood of brachial plexus injuries, hyaline membrane disease etc. OTHER OPTIONS: - Ambiguous genitalia can occur in any of adrenogenital syndromes - Cretinism results from deficiency of thyroid hormone during fetal development & during postnatal life. - Sheehan syndrome occurs in mother d/t ischemic injury to pituitary following delivery resulting in pan-hypopituitarism & has no relationship to diabetes.

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