Anatomy Other topics and Adverse effects b49af6fa Phenytoin pharmacokinetics is highlighted by which of the following characteristics? A High first pass metabolism B Nonsaturation kinetics of metabolism C Capacity limited metabolism saturating at higher therapeutic concentration range D Extrahepatic metabolism High-Yield Explanation (Ref: KDT 6/e p404) Phenytoin follows zero order kinetics at high plasma concentration due to saturation of metabolic pathways.