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Pharmacology General b47511f8

Sedative with GABA facilitating action but without anticonvulsant and muscle relaxant propeies and no effect on sleep ?

A
Diazepam
B
Zolpidem
C
Phenobarbitone
D
Buspirone
High-Yield Explanation
Ans. is 'b' i.e., Zolpidem Among the given options, three are sedative-hypnotic with GABA facilitatory action - Diazepam (a benzodiazepine) - But it also has anticonvulsant and muscle relaxant propey. it) Phenobarbitone - But it has anticonvulsant propey. Zolpidem Has no anticonvulsant and muscle relaxant propey and have no effect on sleep architecture. Zolpidem Zolpidem is a non-benzodiazepine hypnotic. Minimal suppressive effect on REM sleep architecture is not disturbed.

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