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Pharmacology Anesthesia b467167b

Eutectic lignocaine-prilocaine has the following unique propey

A
It causes motor blockade without sensory block
B
By surface application, it can anaesthetise unbroken skin
C
It is not absorbed after surface application
D
It has strong vasoconstrictor action
High-Yield Explanation
Eutectic lidocaine/prilocaine:- This is a unique preparation which can anaesthetise intact skin after surface application. Eutectic mixture refers to lowering of melting point of two solids when they are mixed. This happens when lidocaine and prilocaine are mixed in equal propoion at 25degC. The resulting oil is emulsified into water to form a cream that is applied under occlusive dressing for 1 hr before i.v. cannulation, split skin graft harvesting and other superficial procedures. Ref:-kd tripathi; pg num:-366

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