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Pathology Inflammation & Repair b3d3c9b9

Th1 cells produce?

A
IL-1
B
IL-2
C
IL-4
D
IL-5
High-Yield Explanation
Ans. (b) IL-2(Ref: Inflamm Bowel Dis. 1999 Nov;5(4):285-94)Type 1 T helper (Th1) cells produce interferon-gamma, interleukin (IL)-2, and tumour necrosis factor (TNF)- beta, which activate macrophages and are responsible for cell-mediated immunity and phagocyte-dependent protective responses. By contrast, type 2 Th (Th2) cells produce IL-4, IL-5, IL-10, and IL-13, which are responsible for strong antibody production, eosinophil activation, and inhibition of several macrophage functions, thus providing phagocyte-independent protective responses.

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