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Pediatrics General b3c06f37

6 months old infant with Hb of 6 gm% has anaemic features with peripheral blood showing target cells. Family history of similar complaints is (Positive). Diagnosis can be best done with which of the following –

A
Hb electrophoresis
B
ELISA
C
Coomb's Test
D
Osmotic fragility
High-Yield Explanation
Presence of : Anaemia (Hb < 6%),   Target cells, Increase reticulocytes suggests the diagnosis of thalassemia. Thalassemia is a hemoglobin disorder. Hemoglobin disorders are diagnosed by electrophoresis. Diagnosis of thalassemia is confirmed by serum electrophoresis.

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