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Biochemistry Metabolism of carbohydrate b367b9cf

Which of the following enzyme does not catalyse the irreversible step in glycolysis

A
Hexokinase
B
Phosphoglycero kinase
C
Pyruvate kinase
D
Phosphofructokinase
High-Yield Explanation
Glycolysis Site of occurrence Cytosol Aerobic glycolysis Glucose - Pyruvate ; 8 ATP Anaerobic glycolysis Glucose - Lactate ; 2 ATPReaction occurring in aerobic conditions only Glyceraldehyde 3 phosphate - 1,3- bisphosphoglycerate Inhibitors Glyceraldehyde 3 phosphateIodo acetate 1,3 bisphosphoglycerate Arsenite Enolase Fluoride Glycolysis TCA cycle Malate shuttle ( Liver , Hea , Kidney )38 ATP / 32 ATP ( new )Glycolysis TCA cycle Glycerophosphate shuttle ( Brain , White skeletal muscles )36 ATP / 30 ATP ( new )Irreversible reactions Reactions Enzymes Glucose - Glucose-6-phosphateHexokinase Fructose-6-phosphate - Fructose-1,6,bisphosphatePhosphofructokinasePhosphoenolpyruvate - Pyruvate Pyruvate kinase Oxidative / Substrate level phosphorylation Reactions Enzymes 1,3- bisphosphoglycerate - 3 phosphoglyceratePhosphoglycerate kinase Phosphoenol pyruvate - Pyruvate Pyruvate kinase Harper's illustrated Biochemistry , 30th ed , page 172

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