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Microbiology General b2fc0a3f

Which of the following is the mechanism of action of tetanospasmin ?

A
Inhibition of release of GABA and glycine
B
Inhibition of Ach release from synapse
C
Inhibition of protein synthesis
D
Activation of adenylyl cyclase
High-Yield Explanation
Ans. is 'a' i.e., Inhibition of release of GABA and glycine Pathogenicity CL tetani has little invasive propey and is confined to the primary site of lodgment. Tetanus results from the action of the potent exotoxin it produces.

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