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Medicine General b2ea8534

While handling a febrile neutropenic patient all are essential vccpf :

A
Repeated hand washing of hospital person
B
White cell infusion
C
Prophylactic antibiotic
D
Colony stimulating factor for macrophages
High-Yield Explanation
Answer is B (White cell infusion) While all might be used, the best to be eliminated here is a 'white cell transfusion' as its exact role is yet to be established. White cell infusion (transfusion) as a measure is still controversial- Harrison Neutropenic patients are highly susceptible to infections, and therefore, surgical cleanliness is the first step to ensuring a decreased infection potential - Repeated hand washing Prophylactic antibiotics are ceainly required. Patients with luekopenias and leukocyte dysfunction often have delayed inflammatory responses to infection. Therefore clinical manifestations may be minimal despite overwhelming infection. This necessitates early and prompt institution of prophylactic antibiotics at the earliest suspected sign of infection. Prolonged antibiotics are often required. Recombinant G-CSF and M-CSF is indicated in the management of ceain forms of neutropenia due to depressed production. These enhance granulocyte recovery specially that after chemotherapy and consequently shoen the period of maximal vulnerability to fatal infections. Other agents used include INF which non specifically enhance phagocytic cell function and sho courses of Glucocoicoids. White cell infusion (transfusion) as a measure is still controversial- Harrison Thus while all might be used, the best to be eliminated here is a 'white cell transfusion' as its exact role is yet to be established, and its role is still controversial.

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