True about rectal Ca
High-Yield Explanation
Although rare, the incidence of anal squamous cell carcinoma (SCC) is rising, with a direct association with HPV infection, AIN and immunosuppression. Thus, high-risk groups are those infected with HPV (especially subtypes 16, 18, 31 or 33) Ref: Bailey & Love&;s Sho Practice of Surgery,E25,Page-1269