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Ophthalmology General b2126c73

Cataract in diabetic patients is because of the accumulation of sorbitol in the lens. The enzyme responsible for this is –

A
Hexokinase
B
NADPH+ dependant aldolase reductase
C
Glucokinase
D
Phosphofructo isomerase
High-Yield Explanation
NADPH+ dependent aldolase reductase reduces excessive glucose to sorbitol and intracellular accumulation of sorbitol causes osmotic changes resulting in cataract development.

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