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Pharmacology C.V.S b21256ef

Drug not useful in emergency condition in pregnancy:

A
Nifedipine
B
Labetalol
C
Ritodrine
D
Phenobarbitone
High-Yield Explanation
Ref: Katzung, 14th ed. pg. 203-204; KDT, pg. 323* Nifedipine is a calcium channel blocker which is used as an alternative drug for premature labor.* Influx of calcium ions plays an important role in uterine contractions. CCB's reduce tone of myometrium and oppose contractions.* These drugs, especially Nifedipine can postpone labor only if started early enough.* In emergency situation, Ritodrine (b2 selective agonist) is considered as the drug of choice to suppress preterm labor.* Drug of choice for hypertension in pregnancy- LABETALOL* Drug of choice for epilepsy in pregnancy- Lamotrigine* DOC for status eclampticus in pregnancy - phenobarbitone

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