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Pathology Chemical Mediators and Regulators of Inflammation b206e753

IL2 is secreted by?

A
Neutrophills
B
Helper T-cells
C
Macrophages
D
NK cells
High-Yield Explanation
Ans. is 'b' i.e., Helper T-cells o IL-2 is secreted by lectin- or antigen-stimulated helper T cellsSelected important cytokinesNameMajor Cellular SourceSelected Biologic EffectsIFN-a, -bLeukocytes (IFN-a), fibroblasts (IFN-b)Antiviral, pyrogenicIFN-( interferon)T cells, NK cellsActivates mononuclear phagocytesTNF-a (tumor necrosis factor alpha)Macrophages, NK cellsCell activation, fever, cachexia, antitumorTNF -b (tumor necrosis factor beta), LT (lymphotoxin)T cells, B cellsActivates leukocytes, antitumorIL-1 (interleukin - 1)Macrophages, epithelial cellsT cell and macrophage activation,fever, cachexiaIL-2 (interleukin - 2)T cells (CD4 Helper T-cells)T cell growth and activationIL-3 (interleukin - 3)T cells, thymic epithelial cellsHematopoiesisIL-4 (interleukin - 4)T cells, mast cells, NK cellsB cell proliferation and switching to IgEIL-5 (interleukin - 5)T cellsDifferentiation of eosinophils(NEET)IL-7 (interleukin - 7)Bone marrow stromal cellsLymphoid progenitor differentiation

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