Anatomy All India exam b10fa62f

All are examples of competitive enzyme blockage except

Cyclooxygenase by Aspirin

Thymidylate synthase by 5-FU

Coagulation by Dicumarol

DHFR by Methotrexate

High-Yield Explanation

Kinetics of enzyme inhibition Competitive inhibitionNon competitive inhibitionKm Increased No change V max No change Decreased Significance Drug action Toxicological (Refer: Harper's Illustrated Biochemistry, 26th edition, pg no: 67-68)

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