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Skin General b0c9b299

A 43 year old female presented with pigmentation on neck, axilla and other flexures. She is diabetic for few years and not under control. She is worried about the chance of skin cancer. All of the following are premalignant conditions, EXCEPT:

A
Solar keratosis
B
Acanthosis nigricans
C
Bowen's disease
D
Porokeratosis
High-Yield Explanation
Acanthosis nigricans is probably the most readily recognized skin manifestation of diabetes and most cases are linked to obesity and insulin resistance. True association is rare between acanthosis nigricans and malignancy. It presents as brown to gray-black papillomatous cutaneous thickening in the flexural areas, including the posterolateral neck, axillae, groin, and abdominal folds. Ref: Kalus A.A., Chien A.J., Olerud J.E. (2012). Chapter 151. Diabetes Mellitus and Other Endocrine Diseases. In L.A. Goldsmith, S.I. Katz, B.A. Gilchrest, A.S. Paller, D.J. Leffell, N.A. Dallas (Eds), Fitzpatrick's Dermatology in General Medicine, 8e.

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