Non specific esterase in present in -

Ans. is 'd' i.e., AML Acute myelogenous leukemia (AML) o AML is a cancer of myeloid line of WBCs, characterized by the rapid proliferation of abnormal cells which accumulate in the bone marrow and interfere with the production of normal blood cells. o AML is the most common acute leukemia affecting adults. o The diagnosis of AML is based on finding that myeloid blasts make up more than 20% of the cells in the marrow. o Myeloblasts are mveloperoxidase (peroxidase positive) o Auer rods (represent abnormal azurophilic granule) are also present in myeloblasts and their presence is taken to be definitive evidence of myeloid differentiation. o In some AMLs, blast cells exhibit differentiation of other myeloid stem cell line (other than myeloblast), e.g., (i) Monoblast -3 Lack auer rods, peroxidase negative, but nonspecific esterase positive. (ii) Megakaryocytic differentiation (iii) Erythroblast