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Pharmacology General af6f3e57

ATT most commonly implicated in causing peripheral neuropathy are:

A
Rifampicin
B
Pyrazinamide
C
INH
D
Ethambutol
High-Yield Explanation
Peripheral neuritis and a variety of neurological manifestations (paraesthesias, numbness, mental disturbances, rarely convulsions) are the most important dose-dependent toxic effects of INH. These are due to interference with the utilization of pyridoxine and its increased excretion in urine.

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