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Medicine Immunology and Rheumatology af6688b1

A 67-year-old woman develops symptoms of cough and sputum production after an upper respiratory tract infection. A CXR does not show any signs of pneumonia but the report mentions a "pseudo fracture" sign (Looser zones) seen in the left scapula compatible with osteomalacia. She has no pain in the scapula. Which of the following best differentiates rickets and osteomalacia?

A
the mineralization defect is less severe in osteomalacia
B
Osteomalacia is only produced by vitamin D deficiency, unlike rickets
C
the skeleton is at a different stage when affected
D
parathyroid hormone levels are only routinely elevated in rickets
High-Yield Explanation
Both rickets and osteomalacia are disorders in which mineralization of the organic matrix of the skeleton is defective. Rickets is the name when this disorder occurs in a growing skeleton, whereas osteomalacia occurs after the epiphyseal plates are closed.

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