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Pathology General pathology af14b6e7

Not true regarding Waldenstrom&;s macroglobulinemia,

A
Lymphadenopathy is usually present
B
Blood viscosity increased
C
Ig M immunoglobulin increased
D
Hypercalcemia
High-Yield Explanation
WALDENSTROM'S MACROGLOBULINEMIAIt is a malignancy of lymphoplasmacytoid cells that secreted IgM. In contrast to myeloma, the disease was associated with lymphadenopathy and hepatosplenomegaly, but the major clinical manifestation was hyperviscosity syndrome.Reference: Harrison&;s principles of Internal Medicine; 19th edition; Chapter 136 Plasma Cell Disorders

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