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Gynaecology & Obstetrics General af04833a

Hypogonadotropic primary amenorrhoea is treated by?

A
Gonadotropin therapy
B
Estrogens and progesterone
C
Assisted reproductive techniques
D
None of the above
High-Yield Explanation
Ans. is 'a' i.e., Gonadotropin therapyTreatment of Hypogonadotropic Primary Amenorrhoea:These women have FSH level less than 40 mIU/mL.Hypogonadotropinaemia leading to hypogonadism is usually the result of hypothalamic dysfunction, pituitary failure or systemic illnesses.Administration of GnRH helps to differentiate hypothalamic dysfunction from pituitary failure. In patients with pituitary failure systemic LH level will not rise after giving GnRH.Empty sella turcica, cause of pituitary failure, is characterized by herniation of subarachnoid membrane into the pituitary sella turcica.Absence of pituitary gland causes absence or low level of FSH and LH.In such patients gonadotropin hormone therapy is required for management of primary amenorrhoea.

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