Irregular acanthosis is seen in :
High-Yield Explanation
Acanthosis - increase in number of cells in the Malpighian or prickle cell layer of the epidermis Increased thickness of the epidermis may result from an increased length of rete ridges or may affect the whole epidermis Acanthosis is commonly accompanied by other histological changes - as hypergranulosis, hyperkeratosis and papillomatosis.May be seen in a wide variety of inflammatory and neoplastic disorders. Irregular acanthosis - Lichen planus(saw tooth acanthosis) Regular acanthosis - Chronic eczema , psoriasis