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Physiology Functional Anatomy - Respiratory System ad6a133f

SESSIOH-8Pulmonary surfactant is secreted by -

A
Type I pneumocytes
B
Type II pneumocytes
C
Clara cells
D
Bronchial epithelial cells
High-Yield Explanation
Ans. is 'b' i.e., Type II Pneumocytes Surfactanto Surfactant is a Soap-like substance secreted by the tvpe-II pneumocytes of the alveolar epithelium,o It is a mixture of dipalmitoyl-phosphatidycholine (dipalmitoyl-lecithin), phosphatidylglycerol, other phospholipids, neutral lipids, Surfactant proteins A, B, C and D (SP-A, SP-B, SP-C and SP-D), and carbohydrates.o Surfactant reduces the alveolar surface tension. This has three important physiological consequences : -1) It reduces the collapsing tendency of lungs.2 ) It reduces the natural tendency of the smaller alveoli to collapse and empty into the larger ones. This is called alveolar stabilization.3) It reduces the tendency of the alveolar interstitial fluid to transudate out into the alveolar space.o Dipalmitoyl-phosphatidylcholine (dipalmitoyl-lecithin) is the main surface tension lowering phospholipid in surfactant.

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