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Pathology Urinary tract ad318eac

Lupus glomerulonephritis includes-

A
MPGN
B
Mesangeal proliferative GN
C
Focal segmental GN
D
Membranosclerosis
High-Yield Explanation
Morphological classification of lupus nephritis has proven to be clinically useful. Five patterns are recognized: minimal mesangial(class1); mesangial lupus glomerulonephritis (class II); focal proliferative glomerulonephritis (class III); diffuse proliferative glomerulonephritis (class IV);and membranous glomerulonephritis (class V). Mesangial lupus glomerulonephritis is characterized by mesangial cell proliferation and lack of involvement of glomerular capillary walls. It is seen in 10% to 25% of patients, most of whom have minimal clinical manifestations, such as mild hematuria or transient proteinuria. There is a slight to moderate increase in the intercapillary mesangial matrix as well as in the number of mesangial cells. Despite the mild histologic changes, granular mesangial deposits of immunoglobulin and complement are always present. From Pathologic basis of disease ROBBINS, 8th edition, pg no:217

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