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All of the following are true about 5-flurouracil except

A
It is a purine analogue
B
5 - flurouracil acts by inhibiting Thymidilate synthase enzyme
C
It can cause hand & foot syndrome
D
It is used along with folinic acid and oxaliplatin for colorectal cancer
High-Yield Explanation
5-flurouracil is a pyrimidine analogue which is converted to dUMP in the cell and inhibits Thymidilate synthase enzyme. Capecitabine (Prodrug of 5-flurouracil) & 5-flurouracil can cause "Hand & Foot syndrome". FOLFOX  regimen (Folinic acid, 5-flurouracil and oxaliplatin) is the DOC for colorectal cancer.
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