Which of the following drugs is useful for treatment of advanced prostrate cancer

Refer Harrinson 17th 638 The most significant advance in the therapy of sickle cell anemia has been the introduction of hydroxyurea as a mainstay of therapy for patients with severe symptoms Hydroxyurea (10-30 mg/kg per day) increases fetal hemoglobin and may also exe beneficial affects on RBC hydration, vascular wall adherence and suppression of the granulocyte and reticulocyte counts