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Pharmacology Chemotherapy ac7eb3ed

Nightmares are commonly associated with which of the following antiretroviral drugs?

A
Indinavir
B
Zidovudine
C
Tenofovir
D
Eirenz
High-Yield Explanation
Eirenz can be given once daily because of its long half-life (40-55 hours).The principal adverse effects of eirenz involve the central nervous system. Dizziness, drowsiness, insomnia, nightmares, and headache tend to diminish with continued therapy; dosing at bedtime may also be helpful.Others: rash, | liver enzymes, headache, nausea; Psychiatric symptoms such as depression, mania, and psychosis have been observed. Ref: Katzung; 12th edition; Page no: 877

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