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Biochemistry NEET 2019 ac3b955f

Which of the following is increased in LCAT deficiency?

A
HDL
B
LDL
C
VLDL
D
Chylomicron
High-Yield Explanation
LCAT(Lecithin Cholesterol Acyl Transferase,) Conves HDL cholesterol to HDL cholesterol ester by adding one fatty acid in cholesterol. LCAT deficiency Proper HDL is not formed Spherical HDL | Nascent or discoidal HDL | Free cholesterol | ( not getting incorporated in HDL) RBCs have increased cholesterol content and thus hemolysis occurs Disease Norum's disease Fish eye disease LCAT Complete deficiency Paial deficiency Hemolytic Anemia Severe Absent End stage renal disease Present Absent

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