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Pathology Apoptosis abd0e470

Not true about apoptosis -

A
Increase in lysosomal enzyme
B
Increase in caspases
C
Phosphatidyl serine has important role
D
Intemucleosomal cleavage of nucleus
High-Yield Explanation
Ans. is 'a' i.e., Increase in lysosomal enzymeApoptosiso Caspases are central to the pathogenesis of apoptosis.# The lysis in apoptosis is caused due to action of caspase.o Mitochondrias are the most important organelles involved in initiation and regulation of apoptosis.# Hallmark of apoptosis is permeability of the mitochondrial membrane.o formally phosphatidyl serine is located on the inner cytosolic surface of plasma membrane# In apoptotic cell this phosphatidyl serine is translocated to the outer (extracellular) surface of plasma membrane.o Lysosome and other organelles remain intact.

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