Which of the following is not a major criteria for diagnosis of multiple myeloma ?
High-Yield Explanation
In the NCCN guidelines, active multiple myeloma is no longer diagnosed using the CRAB criteria (hyperCalcemia, Renal failure, Anemia, Bone lesions) for end-organ damage. The current diagnostic criteria are as follows : Bone marrow clonal plasma cells >=10% or bony or extramedullary plasmacytoma (confirmed by biopsy)