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Pathology General aad30fd7

True about fragile-X syndrome -

A
Triple nucleotide repeat sequence
B
Chromosome breaking
C
Mitochondrial mutation
D
Centrachrome absent
High-Yield Explanation
Ans. is 'a' i.e., Triple nucleotide repeat sequence Trinucleotide-repeat mutations disorders Expansion affecting coding regions Expansion affecting non-coding regions o Spinobulbar muscular atrophy (Kennedy disease) o Fragile-X syndrome o Huntington disease o Freidreich ataxia o Dentatorubral-pallidaluysion atrophy (Haw river syndrome) o Myotonic dystrophy o Spinocerebellar ataxia

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