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Pathology General aab8936d

Aneuploidy is seen with all except:

A
Trisomy of chromosome 18 and 13
B
Trisomy 21
C
Klinefelter syndrome
D
DiGeorge syndrome
High-Yield Explanation
Aneuploidy is the number of chromosomes which is not an exact multiple of haploid number e.g. hypodiploid or 2N-1 (45 chromosomes) monosomy, hyperdiploid or 2N+1 (47 chromosomes) trisomy. Common syndromes with numerical aberrations: Down’s syndrome: Trisomy 21  Klinefelter’s syndrome: Sex chromosome trisomy - 47, XXY Turner’s syndrome: Monosomy (45, X0) DiGeorge syndrome, also known as 22q11.2 deletion syndrome, is a syndrome caused by the deletion of a small segment of chromosome 22.  Mohan H. Textbook of pathology. Jaypee Brothers Medical Publishers; 2015. Edition 7. Page 253

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