True about effects of on a child's brain

B i.e. Behaviour changes are common Effect of on cognitive functions (i.e. global intelligence, IQ learning, memory, attention and behavior) depends on age (< 3-5 years) of patient, volume of irradiation (CSI) > and dose (36>24>18)Q. - Endocrinal deficiencies (GH>> ACTH and gonadotropin > TSH lit hypothyroidism) can occur d/t irradiation of hypothalamic - pituitary axis. Total dose and differential sensitivity of hypothalamic nuclei are impoant determinant. Hypothalmic obesity, diabetes insipidus and hyperprolactinemia are more often d/t local tumor effects and surgery. Thyroid and ovarian failure often occurs d/t CSI d/t incidental irradiation of these organs. Other long term somatic complications include permanent hair loss, wound healing problems, softening of bone and ligaments of spine and spinal growth impairment and small head size (musculo-skeletal problems)Q.