Which drug are not used in severe persistent Asthma?

Oral coicosteroids are given in very severe persistent asthma and not severe persistent asthma. Sho acting beta 2 agonists are used for emergency management of acute asthma. Regular prolonged usage of S.A.B.A /salbutamol results in tachyphylaxis and tolerance to the effects of the drug. Hence S.A.B.A should be used for symptomatic relief as and when required. L.A.B.A with inhaled high dose steroids is used for the management of severe persistent asthma.