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Biochemistry General aa84169a

Vitamin B1 is required for which reaction

A
Transamination
B
Oxidative decarboxylation
C
Carboxylation
D
All of the above
High-Yield Explanation
Ans. is 'b' i.e.,Oxidative decarboxylation Active form (coenzyme form) of thiamine is thiamine pyrophosphate (TPP), also called thiamine diphosphate (TDP).TPP acts as coenzyme forOxidative decarboxylation:- Pyruvate dehydrogenase, a-ketoglutarate dehydrogenase, brached-chain keto acid dehydrogenase.Transketolase in PPP.

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