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Pharmacology Other topics and Adverse effects a9fe6285

Which of the following statements about terbinafine is FALSE?

A
Its activity is restricted to dermatophytes
B
It is effective in onychomycosis
C
It is not effective in cryptococcal meningitis
D
It is kunlikely to produce anti-androgenic side effects
High-Yield Explanation
(Ref: KDT 6/e p765) Terbinafine is a CIDAL drug against dermatophytes. It can be administered orally or can be applied topically. It acts by inhibiting the enzyme squalene epoxidase resulting in accumulation of toxic squalene.

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