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Pharmacology Anti-HIV Drugs a9f0c5d5

Which of the following binds to viral envelope glycoprotein preventing the conformational changes required for the fusion of viral and cellular membranes?

A
Abacavir
B
Indinavir
C
Enfuviide
D
Oseltamivir
High-Yield Explanation
Enfuviide is a fusion inhibitor useful in the treatment of HIV infections. It acts by binding to HIV-I envelope transmembrane glycoprotein (gp41) which is involved in fusion of viral and cellular membranes. Abacavir is a NI Indinavir is a protease inhibitor Oseltamivir is a neuramindase inhibitor.

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