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Pathology Cardiovascular system a9eda7b0

All are seen in malignant hypeension except

A
Fibrinoid necrosis
B
Hyaline aeriolosclerosis
C
Necrotizing glomerulonephritis
D
Hyperplastic aeriolosclerosis
High-Yield Explanation
Hyaline aeriolosclerosis: It is seen in the aerioles in patients with benign hypeension. * Microscopy: It shows thickening of the wall due to homogeneous, pink hyaline material and narrowing of the lumen (Fig. 9.7A). * Mechanism: Chronic hemodynamic stress produced by hypeension - produces leakage of protein into the vessel wall - increased synthesis ECM by smooth muscle cell - hyalinization of the wall of aeriole. * Consequence: The aeriolar narrowing - impaired blood supply to kidney - produces ischemia and glomerular scarring. The kidney changes in benign hypeension are called benign nephrosclerosis. Manual of pathology of ramadas nayak Edition 1 Pageno.287

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