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Pathology Misc. (R.B.C) a9eb5140

Leptocyte in blood smears seen in?

A
Sickle cell anemia
B
Thalassemia
C
Post splenectomy
D
Uremia
High-Yield Explanation
Ans. (b) Thalassemia(Ref: Robbins 9th/pg 649-652)Leptocytes are flattened red cells in which the volume-to- surface area ratio is decreased. Seen in iron deficiency anemia and thalassemia in which the red cells with a low mean cell hemoglobin (MCH) and mean cell volume (MCV) are unusually resistant to osmotic lysis.

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