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Pharmacology Chemotherapy a9a35e32

Topical mitomycin-C is used in: (REPEAT)

A
Sturge-Weber syndrome
B
Laryngotracheal stenosis
C
Endoscopic angiofibroma
D
Skull base osteomyelitis
High-Yield Explanation
Mitomycin-C is an antineoplastic antibiotic that acts as an alkylating agent by inhibiting DNA and protein synthesis. It can inhibit cell division, protein synthesis, and fibroblast proliferation. Topical application of mitomycin-C (0.4 mg/mL) was used as an adjuvant treatment in the endoscopic laser management of laryngeal and tracheal stenosis. REFERENCE: www.ncbi.nlm.nih.gov

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