Drug induced portal hypertension is seen with -

Normal doses of vitamin A are not associated with liver injury or liver test abnormalities, but higher doses can be toxic Mechanism of Injury • Excess vitamin A is stored in stellate cells in the liver and accumulation can lead to their activation and hypertrophy, excess collagen production, fibrosis and liver injury. • Serum bilirubin is typically only mildly elevated. • Liver biopsy is diagnostic