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Pathology Cellular Responses and Adaptations to Stress a9558864

Eosinophilia in necrosed tissue is due to -

A
Coagulation of proteins
B
Denaturation of enzymes
C
Denaturation of protein
D
Mitochondrial damage
High-Yield Explanation
Ans. is 'c' i.e., Denaturation of protein o Necrotic cells show increased eosinophilia in hematoxylin and eosin (H & E) stains.o It is due to -i.) Loss of cytoplasmic RNA (or ribonucleoprotein/RNP) which binds the blue dye, hematoxylin.ii) Denatured cytoplasmic proteins which bind the red dye, eosin.

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