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Pharmacology Adverse Drug Effect a8e1fa2a

Pulmonary fibrosis is the most common complication after treatment with

A
6- mercaptopurine
B
Vincristine
C
Bleomycine
D
Adriamycine
High-Yield Explanation
Ans. is 'c' i.e., bleomycin This question has been repeated numerous times before so its well-known that Bleomycin causes Pulmonary fibrosisThe other important fact about Bleomycin is its mechanism of action.* It causes DNA chain scission and inhibits repair by intercalating between DNA strands*Other drugs causing pulmonary fibrosis areacyclovir*amiodarone*busulphan*cyclophosphamide*melphalan*methotrexate*methysergide*

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