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Surgery Small & Large Intestine a8d57a01

Teduglutide is a recently introduced drug for Short Bowel Syndrome- What is it?

A
GLP- 2 analogue
B
GLP anta agonist
C
Somatostatin analogue
D
H1 blocker
High-Yield Explanation
Ans. (a) GLP -2 analogueRef: Surgery Sixer 3rd Edition Page 425, Direct lineTeduglutide: GLP-2 analogue:* Randomized controlled trials have shown that teduglutide, a GLP-2 analogue that is resistant to degradation by the proteolytic enzyme dipeptidyl peptidase 4 and therefore has a longer half-life than GLP-2, is well tolerated and has led to the restoration of intestinal functional and structural integrity through significant intestinotrophic and pro absorptive effects.

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