All are true regarding chloroquine, EXCEPT :
High-Yield Explanation
Ans. is 'a' acts only on exoerythrocytic cycle.]Reference KDT 5th p. 739 (4th page 793)]Chloroquine is a rapidly acting erythrocytic schizonticide. It is active against all species of plasmodium.It has no effect on pre and exoerythrocytic phase of the parasite.Mechanism of action of chloroquine :|First chloroquine is concentrated inside infected erythrocytes. (Higher cone in infected RBC).|Prevents the polymerization of heme into hemozoin|Heme damages the plasmodium membrane.About choice "B" K.D.T. says -" The earlier hypothesis that chloroquine acts by interfering with DNA function is now considered untenable"