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Medicine General a8a3e4e9

Risk factors associated with the development of Gout all except

A
Thiazide
B
Alcohol
C
Female sex
D
Hypertension
High-Yield Explanation
Gout is an inflammatory disease caused by deposition of monosodium urate monohydrate crystals in and around synovial joints. Causes of hyperuricaemia and gout Diminished renal excretion Increased renal tubular reabsorption* Renal failure Lead toxicity Lactic acidosis Alcohol Drugs-Thiazide and loop diuretics, Low-dose aspirin, Ciclosporin, Pyrazinamide Increased intake Red meat Seafood Offal Over-production of uric acid Myeloproliferative and lymphoproliferative disease Psoriasis High fructose intake Glycogen storage disease Inherited disorders Lesch–Nyhan syndrome (HPRT mutations) Phosphoribosyl pyrophosphate synthetase 1 mutation

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