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Gynaecology & Obstetrics Diagnosis in Obstetrics a8a2f5fe

Which of the following is not an indication of amniocentesis for chromosomal anomaly detection?

A
Gestation diabetes
B
Previous Down's child
C
Maternal age more than 35
D
Parents with chromosomal anomaly
High-Yield Explanation
Ans, is a, i.e. Gestation diabetesRef. Dutta Obs. 7/e, p 647; Fernando Arias 3/e, p 46, 47; COGDT 10/e, p 107, Williams Obs. 23/e, p 299, 300Amniocentesis or chorionic villi sampling should be offered to the following class of patients:-Singleton pregnancy and maternal age 35 years or above.-Twin pregnancy at age over 31 years of pregnancy.-Previous chromosomally abnormal child.-Three or more spontaneous abortions.-Patient or husband with chromosome anomaly.-Family history of chromosome anomaly.-Possible female carrier of X-linked disease.-Metabolic disease risk (because of previous experience or family history).-NTD risk (because of previous experience or family history).-Positive second-trimester maternal serum screen or major fetal structural defect identified by USG.

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