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Pathology General a83e4672

Bridging necrosis is characteristically seen in:

A
Acute hepatitis
B
Chronic hepatitis
C
Both of the above
D
Nonel of the above
High-Yield Explanation
In severe cases of acute hepatitis, confluent necrosis of hepatocytes may lead to bridging necrosis connecting poal-to-poal, central-to-central, or poal-to-central regions of adjacent lobules. Hepatocyte swelling and regeneration compress sinusoids, and the more or less radial array of hepatocyte plates around terminal hepatic veins is lost. Bridging fibrosis is an impoant component of severe examples of chronic viral hepatitis and steatohepatitis. Ref: Robbins 8th edition Chapter 18.

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