The following feature is most commonly seen in
High-Yield Explanation
Parakeratasis is appearance of nuclei in the stratum corneum, which is normally nonnucleated cell layer. It can be a result of incomplete differentiation in keratinocytes or of reduced transit time. Clinically parakeratosis manifests as scaling, which is typical of papulosquamous disorders.
Actinic keratosis shows atypical pleomorphic keratinocytes in the basal layer, over which acanthosis, hyperkeratosis, and parakeratosis are also found.
Seborrheic keratosis is characterized by uniform basaloid cells, keratin cysts, and a large number of melanocytes.